Intravenous methylprednisolone pulse therapy in severe alopecia areata

comparison of oral prednisolone pulse therapy with intravenous methyl prednisolone pulse therapy in severe alopecia areata

Efficacy and safety of oral mega pulse methylprednisolone for severe therapy resistant Alopecia areata.

OBJECTIVE To use intensive regimen of pulse steroid in the severe forms of Alopecia areata. METHODS This prospective randomized study was conducted at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between 2003 to 2009. Patients with Alopecia universalis, Alopecia totalis, or Alopecia ophiasis were assigned to one of the 3 treatment groups: Group A received oral mega pulse m...

Recalcitrant Widespread Alopecia Areata in a Child Treated Successfully with Oral Methylprednisolone Pulse Therapy

Alopecia areata is a common condition with patchy non scarring hair loss. We report a case of an 11 year old male child with localized patch of hair loss on the frontoparietal region of the scalp since one year. It was a widespread extensive patch of hair loss covering more than 40% of the scalp. On hair shaft microscopy, numerous exclamation mark hairs were present. The patient was put on topi...

severe active ulcerative colitis and resistance to intravenous hydrocortisone therapy: successful treatment with methylprednisolone pulse therapy

ulcerative colitis is a mucosal-inflammatory disease that usually involves the rectum and extends proximally to involve all or part of the colon. medications for treatment include anti-inflammatory agents such as 5-asa compounds, systemic and topical corticosteroids and immunomodulators. a 33 year-old female and 52 year-old male both diagnosed with severe active ulcerative colitis who were resi...

High-dose pulse corticosteroid therapy: is it indicated for severe alopecia areata?

Accessible online at: www.karger.com/journals/drm In this issue of the journal, Seiter and his group report their experience with high-dose pulse corticosteroid therapy in the treatment of severe alopecia areata (AA) [1]. They treated 30 patients with intravenous methylprednisolone on 3 consecutive days at 4-week intervals for at least 3 courses; 67% of their patients with AA plurifocalis showe...